Eisai aims to improve business efficiency and productivity and promptly maximize contribution to patients by leveraging global partnerships.
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*Details of the agreements below are as of the end of March 2021.
Strategic Collaboration
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Party to contract | Date of conclusion | Contract content |
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Biogen (U.S.A.)
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March 4, 2014
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1. Acquisition of option rights for co-development/co-promotion of the Eisaideveloped
anti-amyloid beta(Aβ) protofibril antibody BAN2401 (generic name: lecanemab) and the BACE
inhibitor E2609 (generic name: elenbecestat)*, and co-development/ co-promotion of a Biogendeveloped
anti-tau antibody
2. Co-development/ co-promotion of the Biogendeveloped anti-Aβ antibody
BIIB037 (generic name: aducanumab)
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U.S. Merck |
March 7, 2018
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Co-development/co-promotion of Eisai’s anticancer agent Lenvima as monotherapy and in
combination with U.S. Merck’s anti-PD-1 antibody Keytruda for a number of cancer types
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Nichi-Iko Pharmaceutical Co., Ltd. |
March 28, 2018
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1. Collaboration in building the Company’s Total Inclusive Ecosystem
2. Partnership in the active pharmaceutical ingredient business
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* In September 2019, Biogen and Eisai discontinued Phase III testing to verify the efficacy and safety of E2609 (generic name:
elenbecestat).
Licensing
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Party to contract | Date of conclusion | Contract content |
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Fujifilm Corporation
Toyama Chemical Co., Ltd.
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September 30, 1998
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Joint development of and marketing alliance for the rheumatoid arthritis agent Careram (generic name: iguratimod)
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AbbVie Deutschland GmbH & Co. KG (Germany)
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June 16, 1999 |
Development and sale of the anti-TNF-α monoclonal antibody Humira (generic name: adalimumab) in Japan and South Korea
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Novartis AG (Switzerland)
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February 6, 2004 |
License for worldwide development, manufacturing, and sale of the antiepileptic agent Inovelon (generic name: rufinamide)
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Sunovion Pharmaceuticals Inc. (U.S.A.)
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July 26, 2007 |
Exclusive license for the development and marketing of the insomnia treatment Lunesta (generic name: eszopiclone) in Japan
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BioArctic (Sweden)
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December 3, 2007 |
Exclusive license for worldwide research and development,manufacturing, and sale of the anti-Aβ protofibrils antibody BAN2401 (generic name: lecanemab) for the treatment of Alzheimer’s disease
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Pfizer Inc. (U.S.A.)
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September 24, 2009 | Co-promotion agreement in Japan for the pain treatment agent Lyrica (generic name: pregabalin) |
Prism BioLab Co., Ltd. |
April 1, 2011
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Exclusive license for worldwide development, manufacturing, and sale of the anticancer agent E7386 |
University of London (U.K.)
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October 16, 2015 | Collaborative research and co-development of the anti-tau antibody E2814 |
Meiji Seika Pharma Co., Ltd.
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March 31, 2017 | Licenses related to exclusive sales rights in Japan and exclusive development and sales rights in 7 Asian countries for the anti-Parkinson’s disease agent Equfina (generic name: safinamide) |
Harvard University (U.S.A.)
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June 15, 2018 |
Exclusive license for worldwide development, manufacturing, and sale of anticancer agent E7130
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Gilead Sciences, Inc.
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December 24, 2019
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Marketing alliance contract for the selective Janus kinase 1 inhibitor filgotinib (generic name) in Japan |
Minophagen Pharmaceutical Co., Ltd. |
February 29, 2016
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1. Exclusive development and sales rights of the liver disease/allergic disease agents Stronger Neo- Minophagen C (glycyrrhizic acid, compound formulation) and Glycyron Tablets (glycyrrhizic acid, compound tablet) in China and other parts of Asia
2. Exclusive sales rights of the liver disease/allergic disease agents Stronger Neo- Minophagen C (glycyrrhizic acid, compound formulation)
and Glycyron Tablets (glycyrrhizic acid, compound tablet) in Japan
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* In July 2020, the exclusive development and marketing rights license agreement for the Company’s Stronger Neo-Minophagen
C and Glycyron Tablets were extended until March 31, 2033.
* In February 2021, Eisai Europe Ltd. (U.K.) ended the marketing license agreement and co-promotion agreement of the
antiepileptic agent Zebinix (generic name: eslicarbazepine) in Europe it had concluded with BIAL - Portela & Ca., S.A.
(Portugal).
In August 2019, the contract for development and sale of Humira in Taiwan ended.
Joint Venture
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Party to contract | Date of conclusion | Contract content |
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Ajinomoto Co., Inc. | October 15, 2015 | Integration agreement concerning the splitting off of a portion of Eisai’s business and its subsequent succession by Ajinomoto Pharmaceuticals Co., Ltd. via an absorption-type split, etc. |
Other Contracts Important for Business
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Party to contract | Date of conclusion | Contract content |
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World Health Organization (WHO) (Switzerland)
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January 30, 2012 | Provision of DEC (generic name: diethylcarbamazine) tablets to the WHO free of charge to support its program to eliminate lymphatic filariasis |