- For Print
- May 11, 2012
Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito, “Eisai”) announced today that its U.S. subsidiary Eisai Inc. has expanded the marketing and supply agreement it concluded with Arena Pharmaceuticals GmbH, the Swiss subsidiary of U.S.-based Arena Pharmaceuticals Inc. (Headquarters: California, President & CEO: Jack Lief, “Arena”), in July 2010 for the anti-obesity agent lorcaserin. While the original agreement granted Eisai the exclusive rights to market and distribute lorcaserin in the United States, subject to U.S. Food and Drug Administration (FDA) approval, the expanded agreement now includes 20 countries throughout the Americas, including Mexico, Brazil, and Canada.
Lorcaserin, originally discovered by Arena, is an investigational drug candidate being developed for weight management, including weight loss and maintenance of weight loss, in patients who are obese (BMI>30) or patients who are overweight (BMI>27) and have at least one weight-related co-morbid condition. The lorcaserin New Drug Application (NDA) is currently under review by the FDA, with an assigned Prescription Drug User Fee Act (PDUFA) date of June 27, 2012, which is the target date for the agency to complete its review.
In recent years, obesity has become a major global health problem. With the expansion of the license agreement, Eisai seeks to deliver lorcaserin as a new treatment option to overweight and obese patients across the Americas who need a way to medically manage their weight.
[ Please refer to the following notes for further information on Eisai's presence in the Americas, lorcaserin and Arena Pharmaceuticals, Inc. ]
Public Relations Department,
Eisai Co., Ltd.
< Notes to editors >
1. Eisai's Presence in the Americas
2. About Lorcaserin
Lorcaserin, discovered and developed by Arena, is a new chemical entity that is believed to act as a selective serotonin 2C (5-HT2C) receptor agonist. The serotonin 2C receptor is expressed in the brain, including the hypothalamus, an area believed to be involved in the control of appetite and metabolism. Stimulation of this receptor is strongly associated with reducing hunger and increasing satiety.
3. About Arena Pharmaceuticals, Inc.
Arena Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing oral drugs that target G protein-coupled receptors, an important class of validated drug targets, in four major therapeutic areas: cardiovascular, central nervous system, inflammatory and metabolic diseases.
Arena Pharmaceuticals® and Arena® are registered service marks of the company.