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News Release

November 22, 2001

Notice Received from the European Commission
Regarding Sales of Bulk Synthetic Vitamin E

Tokyo (November 22, 2001) - Eisai Co., Ltd. of Tokyo (President and CEO: Haruo Naito) announced that it has received on November 21st a notice of infringement of competition rules from the European Commission regarding the sales of bulk synthetic vitamin E.

The Company has been fined euro13.23 million (approximately yen1.4 billion). The Company cooperated with an investigation conducted by the European Commission.

The Company is in the process of reviewing the contents of the notice from the European Commission.