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News Release

May 17, 1999

Eisai Launches Sea-Bond A Sheet-Type Denture Adhesive

Tokyo (May 17, 1999) - Eisai Co., Ltd. of Tokyo (President and CEO:Haruo Naito) today announced the launch on May 17 of a sea kelp derived natural sheet-type denture adhesive, SEA-BOND

Because SEA-BOND is a sheet-type denture adhesive, it provides a uniform adhesive distribution. The adhesive, derived from sea kelp,is tasteless, odorless, and provides a safe comfortable, all-day hold. As a sheet-type denture adhesive, SEA-BOND cannot ooze from the dentures. Moreover, the sheet also serves as a cushion that is evenly distributed on the dentures.

SEA-BOND is a convenient to use sheet that is applied to the dentures after being moistened by water. And SEA-BOND peels off easily after usage. SEA-BOND eliminates inconvenience and discomfort and restores confidence and security.

SEA-BOND is manufactured in the U.S. by COMBE Inc. and Tanpei Pharmaceutical has sold SEA-BOND in Japan since 1993. From now Eisai will begin sales of SEA-BOND. In the U.S., SEA-BOND is highly recognized sheet-type denture adhesive.

Suggested Retail Price: Upper, lower denture usage, 18 sheets per package, I850
Sales/Distribution: Eisai Co., Ltd.
Imported by: Takehaya Co., Ltd.
Manufactured by: COMBE Laboratories Incorporated (U.S.A.)

For additional information about SEA-BOND and Eisai's other consumer health care products, please contact Eisai's Consumer Hotline. Toll Free Number (in Japan): 0120-161-454. Monday-Friday 9 a.m.- 8 p.m. and Saturday/ Sunday/ Holiday 9 a.m.- 5 p.m.

Eisai Co., Ltd. is a research-based human health care company which discovers, develops and markets products in more than 30 countries. Through its global network of research facilities, manufacturing sites and marketing subsidiaries, Eisai actively participates in all aspects of the worldwide health care system. The company reported sales of about $2.3 billion in 1997 with approximately 16 percent of sales spent for research and development.

SEA-BOND is a registered trademark of COMBE Incorporated.