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News Release

FOR IMMEDIATE RELEASE
May 15, 2012

Proposed Changes in Representative Officers

Listed Company Name: Eisai Co., Ltd.
Representative: Haruo Naito
Director, President & CEO
Headquarters: 4-6-10 Koishikawa Bunkyo-ku, Tokyo
Securities Code: 4523
Listed Locations: First Sections of the Tokyo Stock Exchange
& the Osaka Securities Exchange
Inquiries: Yutaka Tsuchiya
Executive Vice President
Public Affairs
Phone 81-3-3817-5120

Eisai Co., Ltd. (Headquarters: Tokyo, President & CEO: Haruo Naito) resolved at its Board of Directors meeting held on May 15, 2012 to propose the following changes in its Representative Officers, effective June 21, 2012.

1. Changes in Representative Corporate Officers (effective June 21, 2012)
 a) Retiring Representative Corporate Officers:
   Nobuo Deguchi     currently, Deputy President , Aide to President, Chief Compliance Officer
  *Nominee for New Director

 b) Nominees for New Representative Corporate Officers
  i) Deputy President
   Hideshi Honda     currently, Executive Vice President,
President, East Asia Region
   Hajime Shimizu     currently, Executive Vice President,
President, Indo-Pacific Regions
   Hideki Hayashi     currently, Executive Vice President,
Chief Product Creation Officer, Eisai Product Creation Systems, Investor Relations
  ii) Executive Vice President
   Yutaka Tsuchiya     currently, Executive Vice President,
Corporate Regulatory Compliance, Safety and Quality Assurance,
Public Affairs

2. Career Summary of Nominees for New Representative Officers
Name:    Hideshi Honda
Date of Birth: October 9, 1954
Apr. 1977     Joined the Company
Apr. 2003     Senior Director, International Business and Development Department
Jun. 2003     Executive Officer
Apr. 2004     Deputy General Manager, Global Pharmaceuticals Business Headquarters
Jun. 2004     Vice President
Jun. 2005     General Manager, Consumer Health Product Division
Apr. 2007     Assigned to Japan Business Headquarters
Jun. 2007     Senior Vice President
Jun. 2010     Executive Vice President (current)
Jun. 2010     President, Eisai Japan
Apr. 2011     President, Eisai East Asia Region
Apr, 2012     President, East Asia Region, and Chairman of the Board, Eisai China Inc. (current)
No. of Company shares held: 5,905 (as of Mar. 2012)


Name:    Hajime Shimizu
Date of Birth: April 20, 1957
Apr. 1981     Joined the Company
Jun. 2001     Senior Director, Corporate Management Planning Department
Jun. 2002     Deputy President, Eisai Inc.
Apr. 2004     Chairman & CEO, Eisai Inc.
Jul. 2004     President, Eisai Corporation of North America
Jun. 2006     Vice President (Eisai Co., Ltd.)
Jun. 2006     Assigned to Pharmaceuticals Business, U.S.
Jun. 2007     Senior Vice President
Jan. 2008     Chairman & CEO, Eisai Corporation of North America
Aug. 2009     President, Eisai Corporation of North America
Jun. 2010     Executive Vice President (Eisai Co., Ltd.; current)
Jun. 2010     Assigned to New Markets
Apr. 2011     Assigned to New Markets & ASEAN
April, 2012     Assigned to President, Indo-Pacific Region (current)
No. of Company shares held: 8,438 (as of Mar. 2012)


Name:    Hideki Hayashi
Date of Birth: November 22, 1957
Apr. 1981     Joined the Company
Apr. 2004     Senior Director, Business Development Department
Jun. 2005     Vice President
Jun. 2006     Assigned to Business Development
Jun. 2007     Senior Vice President
Jul. 2009     Chief Product Creation Officer (current)
Jun. 2010     Executive Vice President (current)
Jun. 2011     Assigned to Investor Relations (current)
No. of Company shares held: 4,103 (as of Mar. 2012 )


Name:    Yutaka Tsuchiya
Date of Birth: June 29, 1952
Apr. 1975     Joined the Company
Apr. 2001     Senior Director, Clinical Research Planning Department, Clinical Research Center
Oct. 2004     President, Eisai Europe Ltd.
Jun. 2005     Vice President
Jun. 2006     Assigned to Pharmaceuticals Business, Europe
Mar. 2008     Chairman & CEO, Eisai Europe Ltd.
Jul. 2009     Assigned to Corporate Regulatory Compliance, Quality Assurance,
Environmental and Safety Affairs (Eisai Co., Ltd.)
Jun. 2009     General Manager, Corporate Regulatory Compliance,
Quality Assurance Headquarters (currently Corporate Regulatory Compliance,
Safety and Quality Assurance Headquarters; current)
Jun. 2010     Senior Vice President
Jun. 2011     Executive Vice President (current)
Jun. 2011     Assigned to Quality Assurance, Public Affairs (current)
No. of Company shares held: 9,288 (as of Mar. 2012)